Malaria will be defeated. However, its elimination and eventual eradication will require developing multi-sector partnerships and responses, investing in health and information systems, and placing communities at the center of the design and scale-up of high impact interventions for vector control and delivery of malaria services. We work with stakeholders at all levels of governance to build their ability to design, plan, and implement evidence-driven malaria control activities. In this way, these groups can mobilize and use resources across sector and build responsive supply chain systems that maximize health and economic impact.